Somewhere on here, we've talked about my Alma Mater (University of Georgia) and the mascot -- an English Bulldog (or Bulldawg, as we spell it and it down here!) who is always named "UGA" (followed by a roman numeral). All (or most, at least) of the bulldogs have been related -- anyway, I think this article might just indicate what overbreeding does:

Uga VIII battling lymphoma